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186 The pronounced lack of renal reabsorption of filtered urate in hypouricemic patients with GLUT9 loss-of-function mutations provides compelling evidence of the critical role this protein plays in renal tubular urate reabsorption

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It is not only a key player in thyroid hormone synthesis but also the main autoantigen targeted in autoimmune thyroid diseases (AITDs), making it a focal point for In Vitro Diagnostic (IVD) development