Yeah, so this has been done in humans
Department of Justice, Diversion Control Division IGF-1 LR3: More Affordable but Research-Only IGF-1 LR3 is not FDA-approved for human use , and it is typically labeled for research purposes only. However, its widely available through peptide and research chemical suppliers
After cleansing, toning and applying serums, apply 1-2 pumps to the face and neck area 1-2 times daily or as needed
storage and reconstitution guidance CDC Vaccine Administration: Subcutaneous Injection Subcutaneous injection technique (45 angle, pinch skin, no aspiration) European Journal of Endocrinology Ipamorelin GH selectivity Potent and specific GH release without affecting cortisol, prolactin, or FSH/LH PubMed Pharmacokinetic-pharmacodynamic modeling of ipamorelin Human GH release peaked ~0.67 h post-dose JAMA Tesamorelin for Abdominal Fat in HIV Phase 3 trials demonstrating visceral fat reduction with tesamorelin CDC Vaccine Administration During General subcutaneous route guidance (angle/site) NCBI Bookshelf Best Practices for Injection Asepsis, preparation, and administration guidance Additional Research and Background These sources provide related context and are not presented as support for a specific statement above
Skin brightening effects (systematic review) Sonthalia S et al