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The main interest is around tendon, ligament, muscle, gut lining, connective tissue, and general tissue-response biology

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Dipeptidyl peptidase IV (CD26) on T cells cleaves the CXC chemokine CXCL11 (I-TAC) and abolishes the stimulating but not the desensitizing potential of the chemokine

The treatment is generally well-tolerated under medical supervision, though some individuals may experience mild, transient gastrointestinal effects as the body adapts