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However, the co-primary endpoints of a reduction of SLE disease activity index (SLEDAI-2K) and adjusted mean SLEDAI (AMS) in patients compared with controls using a landmark analysis were not met

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In an experimental autoimmune encephalomyelitis model, dexamethasone treatment significantly increased MANF expression in the myelin regions of spinal cord white matter, highlighting its potential as a therapeutic target for MS [150]

ORCID ID Taciana DalForno Dini: 0000-0003-0848-9042 Rafaela Malmann Saalfeld: 0009-0008-0157-0300 Clayton Luiz Dornelles Macedo: 0009-0006-9058-9147 Edileia Bagatin: 0000-0001-7190-8241 Research data availability The entire dataset supporting the results of this study was published in this article