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Nevertheless it seems that the Fab-bound conformations of GCGR and GLP-1R are different

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This will largely depend on the target populationidiopathic PD versus specific phenotypes/genotypesbut in general, an inclusive approach would be desirableage, sex, ethnicitycomplemented by enrichment of specific treatment arms according to the compounds mode of action, to progress towards precision medicine [48, 49]

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