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Increasing glutathione levels can provide significant health benefits by supporting function, reducing oxidative stress, and promoting a healthy immune response

Nat Commun 8 , 16087 (2017)

Primary cultures of satellite cells were prepared from the upper hindlimb and back muscles of 910 month-old male rats and cultured for 24 h beginning at 24-h post-plating in DMEM-10% HS containing 5 ng/ml HGF that was pre-treated with GSSSG and LASSS separately at 1:4000 molar ratio just prior to peroxynitrite treatment (1:2000 to HGF

Jackson et al., 2022)

Having established a strong link between glutathione deficiency and ED, it can be concluded that either men with ED have an inherent defect in glutathione production, or more likely, men with ED have a lower intake of dietary antioxidants that keep glutathione in the reduced state