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The enzyme glutathione reductase, which requires NADPH as a cofactor, recycles GSSG back to GSH, maintaining this ratio [2]

the first 164 residues in GPX1 and 169 residues in GPX7 from N-terminal site contained the transit peptides (Mullineaux et al., Arabidopsis GPX2 and GPX4 were reported to be 169 and 170 residues, respectively with cytosolic localization: thereby, they did not contain any transit peptide (Lin et al., Arabidopsis GPX3 and GPX6 were 206 and 232 residues, respectively, with mitochondrial localizations

Mitochondrial glutathione, a key survival antioxidant

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Author contributions Conceptualisation: AB, AW