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At the beginning of the treatment, 1 ml of vitamin B12 Wiedemann 1 mg/ml (corresponding to 1000 g cyanocobalamin) is administered twice a week in the first weeks after diagnosis Wiedemann Vitamin B12 1 mg/ml contains sodiumbut less than 1 mmol (23 mg) sodium per 1 mli.e

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After three decades and more than two hundred papers, there is still no published randomized controlled trial showing efficacy