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Although cholecystitis has been reported, large outcome trials have not substantiated pancreatitis signals, and current evidence does not indicate increased risks of infection or obesity-related cancers

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Most ephedrine/pseudoephedrine-induced manic episodes involve a pre-existing mood disorder history, suggesting that ephedrine may exacerbate pre-existing mood disorders, or precipitate a previously unproven one [101,102,103,104]

This has contributed to a significant increase in demand for and interest in GLP-1RAs around the world

Practical supports are the ones that let you detect change early: Frequent weight checks Simple glucose logs if relevant Short follow-up visits in the first few weeks Clinicians may discuss alternative options such as different GLP-1 agents or combination therapies if weight or glucose control slips