SGLT inhibitors In several Phase III programmes in people with type 1 diabetes, the use of SGLT-1 or SGLT-1/2 inhibitors reduced HbA 1c , improved TIR, reduced body weight and improved blood pressure [244]
A: Start with one
Endocrinology 156 (1), 90102 (2015)
Work with Your Healthcare Provider Regular follow-up appointments allow your provider to monitor your progress, adjust your dose if needed, manage side effects, and provide support throughout your weight loss journey
A GP, pharmacist, or specialist clinician can: Review your current medication list for potential interactions, particularly with diabetes medications, anticoagulants, thyroid treatments, and hormonal contraceptives Assess your nutritional status and advise on appropriate supplementation only where deficiencies are confirmed Monitor for adverse effects such as hypoglycaemia, gastrointestinal disturbance, or unexpected changes in blood pressure or heart rate Refer you to appropriate NHS services , including Tier 3 weight management programmes, if you are seeking structured support for obesity Discuss contraception and family planning , as retatrutide should not be used during pregnancy or breastfeeding