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Beyond these acute prandial changes, longer-term dietary patterns also play a role

10.1152/ajpcell.00031.2013 106 MandalD.MazumderA.DasP.KunduM.BasuJ

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This study suggests a possible role of ghrelin in pathogenesis of anorexia occurring in advanced liver failure patients.104,105 Discussion As firstly described, food intake and energy expenditure are regulated by hormones released from the gut and adipose tissue, which act on CNS creating a link and feedback mechanisms that allows a maintenance of a steady body weight despite daily variation of energy expenditure and nutrient intake

Handbook of Experimental Pharmacology 168 :1-51