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Glutathione is especially important in defending against oxidative stress, a major driver of many ocular conditions

To synthesize the dimeric macrocycles, a 22-mM solution of the respective C-terminal cysteine-modified monomer peptide in DMSO was incubated with 10 mM of the bis-maleimide linker in 50 mM Hepes-HCl (pH 7.5) with 90% (v/v) DMSO

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