do you lose more weight with semaglutide or tirzepatide Comparing and for Loss: A Rochester M.D.'s View Tirzepatide vs Semaglutide: Which Weight

However, the greater reduction of weight loss with semaglutide vs canagliflozin in the primary SUSTAIN 8 trial [17], when also taking into account the lack of statistical difference in body composition changes between treatments in this substudy, highlights the potential value of semaglutide in terms of weight management in individuals with uncontrolled type 2 diabetes on stable-dose metformin therapy

Dose adjustments of insulin or sulfonylureas are often necessary when starting or stopping semaglutide to mitigate hypoglycemia risk

Stopping medication means managing diabetes through other means, often requiring multiple medications with their own side effects and costs

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doi: 10.7326/M20-0864 121 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFEENauckMAet al