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With dose reduction, the timeline is not well documented but would be expected to fall somewhere between discontinuation and continued use

They were randomly assigned into three groups: semaglutide very low-calorie diet 800 calories per day semaglutide plus very low-calorie diet

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Semaglutide works by mimicking the GLP-1 hormone naturally produced in the body

Then, 30 years later, they tested the participants cognitive abilities multiple times over a span of 2 years (a total of 5 tests)