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Two-way analysis of variance (ANOVA) or Multiple unpaired t tests were used for comparison between multiple groups, the Tukeys multiple comparisons or Holm-dk tests were used to correct the p -values for each group, respectively

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3 to 4 weeks: A clear slimming effect will be present, and the area will appear more defined and sculpted

6b), no significant changes in expression of Gip , Cck , Pc1 (also known as Pcsk1 ), proglucagon and peptide YY mRNA transcripts were observed in the upper or lower gastrointestinal tract of metformin-treated Ppar +/+ and Ppar / mice (Fig