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doi: 10.3389/fnut.2023.1263853 31 RuaRMNogalesFCarrerasOOjedaML

This system categorizes biomarkers as indicators of amyloid pathology (A), tau pathology (T), and neurodegeneration (N)

Oxidation of disulfide bonds of Pt GSTF8 Disulfide bonds between C13 of purified apo- Pt GSTF8 variants and GSH were formed by incubating 20 M Pt GSTF8 with 0 mM or 1 mM GSSG in the presence of 200 M GSH in 10 mM MOPSO, pH 6.45 for 2 h at 30 C, 800 rpm using a 3 mm shaking diameter

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This necessitates frequent dosing for sustained effects but provides rapid clearance that minimizes accumulation risks