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Currently, there are other dual GIPR/GLP-1R agonists available, such as GLP-1R/GR (glucagon receptor), GLP-1R/AR (amylin receptor), and GLP-1R/NPYR (peptide YY binds to neuropeptide Y receptors) [36, 115] and even triple agonists that can activate GIPR to treat obesity and T2DM

However, drinking large amounts of fluid close to bedtime increases nighttime bathroom trips that fragment sleep

Now imagine layering that problem onto patient populations where adherence is the whole game

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The 7.2mg dose is for those who have tolerated the 2.4 mg maintenance dose well and may benefit from a higher strength