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However, the role of GLP-1 receptor antagonists, such as exendin-(9-39), is also of significant interest, particularly in understanding the physiological and therapeutic implications of GLP-1 signaling

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Semaglutide, as a GLP-1R agonist, works very similarly to GLP-1 by potentiating glucose-stimulated insulin secretion from the pancreatic -cells while suppressing glucagon secretion by pancreatic -cells [103]

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