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Previous studies have shown that Epidermal Growth Factor Receptor (EGFR), CD44v (an adhesion molecule expressed in cancer stem-like cells) and OTU deubiquitinase, ubiquitin aldehyde-binding 1 (OTUB1), control and stabilize SCL7A11 expression, facilitating Cys uptake by tumor cells (Tsuchihashi et al., 2016

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However, frequent adverse effects, such as hepatotoxicity, limit its use

Researchers may evaluate GLP-1 receptor systems in controlled models to better understand how peptide structures relate to receptor interaction, pathway selectivity, protein expression, and biochemical signaling