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Another study indicated that patients with major depressive disorder exhibit higher serum IGF-1 levels compared to healthy controls, and the pharmacological treatment of depression reduces IGF-1 levels (111)

Proteostasis: maintenance of protein homeostasis in cells, involving processes that regulate protein synthesis, folding, degradation, and clearance to ensure proper protein function and prevent cellular dysfunction and disease

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For some context, I interviewed Chris several months ago in Dubai, and standing next to him sucks, because he is an absolute beast