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The exact mechanism by which your skin lightening treatment works will vary depending on the type or types of treatments that are incorporated into your treatment plan, and can be discussed during your consultation with Dr
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Specifically, TSH induces hepatic steatosis by activating sterol regulatory element-binding protein (SREBP) pathways, inhibits bile acid synthesis by suppressing the SREBP2hepatocyte nuclear factor 4 (HNF4)CYP7A1 axis, and attenuates cholesterol biosynthesis via AMP-activated protein kinase (AMPK)dependent phosphorylation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) (42)
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