glp 1 and eye disease Possible Link Between GLP-1 RA Medications & Health Diabetes Weight Loss Drugs May

Lancet 365 , 15521560 (2005)

The delayed gastric emptying caused by GLP-1 agonists might compound existing digestive changes, though this interaction has not been systematically studied in large populations

More serious but rare risks include pancreatitis, gallbladder disease, and in diabetes patients, potential worsening of diabetic retinopathy (particularly with semaglutide)

70 Moreover, disc compression induced persistent expression of activating transcription factor 3a, a nerve injury marker, and regeneration of the afferent fibers innervating IVDs

When these processes are compromised, toxins and histamine accumulate, triggering inflammation in the gut lining and increasing sensitivity to foods