reach study semaglutide A, Trial design. was self-injected once weekly with the Frontiers | Safety of Semaglutide

Monitor medication side effects by checking gastrointestinal issues, heart health, blood sugar levels, and mental health

Some patients may benefit from slower dose escalation or temporary dose reduction of their GLP-1 medication if constipation becomes problematic, though this should only occur under medical supervision

These symptoms frequently manifest during the initial treatment phase, affecting approximately 50% to 60% of patients [8], but they generally diminish over time, with their occurrence being dose-dependent

doi: 10.1007/s00125-019-4946-6 10 SorliCHarashimaSTsoukasGMUngerJKarsblJDHansenTet al

The SELECT trial showed Wegovy reduced major cardiovascular events by 20% in people with overweight or obesity and established heart disease