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Note that the treatment protocol of 3 days of treatment followed by 11 days off is much lower than that recommended in the Physician Desk Reference for moderate/severe lead poisoning (21 days of continuous treatment), so it is expected that the treatment regimen used in this study would have fewer side-effects than for a 21-day treatment regimen

Independent verification at every stage

Further randomized and well-controlled studies are needed to confirm these preliminary findings

To view a copy of this licence, visit About this article Cite this article Zhang, J., Liu, M., Ou, H

56 Two longer-term studies, 48 and 52 weeks, respectively, found significant improvements in NAFLD/NASH activity score with NAC, 1200 mg per day, together with metformin