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Int Wound J 13, 572584.CrossRefGoogle ScholarPubMed Prasad, KN, Chaithra, C, Karthik, Y, et al

doi: 10.1086/382893 136 PattersonBKGuevara-CotoJMoraJFranciscoEBYogendraRMora-RodrguezRAet al

To further confirm that celastrol alleviated ferroptosis through the SIRT1-mediated ferroptosis signalling pathway, we used the SIRT1 inhibitor EX527, which was applied at a concentration according to previous studies [30]

Treebak JT, Glund S, Deshmukh A, Klein DK, Long YC, Jensen TE, Jorgensen SB, Viollet B, Andersson L, Neumann D, Wallimann T, Richter EA, Chibalin AV, Zierath JR, Wojtaszewski JF (2006) AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits

These fats are essential because glutathione and certain other vitamins are fat-soluble, meaning the body uses healthy fats to transport and process them effectively