Alvestrand, A., Furst, P
Oxidants = reactive oxygen species (ROS) / free radicals Antioxidants = molecules that neutralise ROS by donating electrons This is fundamentally a REDOX imbalance Free radicals are electron-deficient molecules that: Steal electrons from healthy cells Trigger chain reactions of oxidation Damage: Cell membranes (lipid peroxidation) Proteins (enzyme dysfunction) DNA (accelerated ageing, impaired repair) In SKIN, this translates to: Fine lines & wrinkles Loss of elasticity Pigmentation irregularities Impaired barrier function Chronic inflammation UV radiation ( primary extrinsic ageing factor ) Pollution & cigarette smoke Inflammation (acne, rosacea, dermatitis) Poor sleep & psychological stress Aggressive aesthetic treatments without adequate antioxidant support Antioxidants donate electrons without becoming unstable themselves, effectively terminating free-radical chain reactions and reducing OXIDATIVE STRESS
The proportion of adults worldwide with a BMI 30 kg/m 2 has more than doubled since 1990, and the proportion of adolescents has quadrupled
CRC Press, Boca Raton, pp 199230 Palacios I, Lozano M, Moro C, DArrigo M, Rostagno MA, Martnez JA, Garca-Lafuente A, Guillamn E, Villares A (2011) Antioxidant properties of phenolic compounds occurring in edible mushrooms
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