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If successful, oral tirzepatide could combine the dual-receptor potency of injectable tirzepatide with the convenience of a pill

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These materials overcome limitations associated with traditional nanoparticle-based delivery such as weak tissue penetration, incomplete drug release, and off-target effects by responding to disease-specific microenvironmental cues

In the DAPA-HF, DELIVER and DAPA-CKD trials, safety and efficacy were similar for patients aged 65 years and younger and those older than 65 in both the overall population and in the patients with type 2 diabetes mellitus

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