For AAV-mediated knockdown studies, 8-week-old male C57BL/6 mice received retro-orbital injections of adeno-associated virus serotype 8 (AAV8) carrying either a scramble control or Gpr146-targeting shRNA under the U6 promoter
Back Mentlein, R, Galllwitz, B, Schmidt, WE (June 1993) 'Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36) amide, peptide histidine methionine and is responsible for their degradation in human serum', European Journal of Biochemistry , 214, 829-35
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The reduction of the melanin index with glutathione was statistically significant when compared to placebo [Table - 1]