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Safety profile comparable to GLP-1 agonists when properly titrated [12]

It mimics the effects of GLP-1

Similarly, branched-chain amino acids, such as leucine, isoleucine, and valine, are catabolized in skeletal muscle to produce acetyl-CoA and succinyl-CoA, which enter the TCA cycle and contribute to ATP production

While DCA has shown modest activity in clinical trials, its repurposing potential and low cost make it a candidate for combination therapies

DOI: 10.1001/jamapsychiatry.2020.0246 Rickli A et al (2015): Monoamine transporter and receptor interaction profiles of novel psychoactive substances: Para-halogenated amphetamines and pyrovalerone cathinones