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Injecting too rapidly may increase irritation

Variations and modifications of the present invention will be obvious to those skilled in the art and it is intended to cover in the appended claims all such modifications and equivalents

ACS Chemical Biology, 8 (9), 19121917

While direct evidence for NGFs efficacy in tinnitus patients remains to be established, its established role in neuronal survival, synaptic plasticity, and emotional regulation, combined with emerging bioinformatic evidence of its involvement in tinnitus-related synaptic processes, provides a compelling rationale for further investigating the hypothesis that targeting the NGF/TrkA pathway could simultaneously ameliorate auditory perceptive distortions and the debilitating emotional symptoms that often accompany chronic tinnitus (Gross et al., 2023

Mitochondrial dysfunction promotes compensatory activation of glycolysis, while the accumulation of glycolytic intermediates and metabolites amplifies inflammatory signaling