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Terreic acid is a quinone epoxide antibiotic and a potent Btk inhibitor, blocking the interaction between PKC and the PH domain of Btk.T Terreic acid also acts on HMC-1 human mast cell lysates, inhibiting the binding of GST-BtkPH to PKC with an IC50 of approximately 100 M

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[DOI] [PubMed] [Google Scholar] 53.Conquet P., Plazonnet B., Le Douarec J.C

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