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Wegovy (semaglutide 2.4 mg) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed by the MHRA and recommended by NICE (TA875, 2023) for managing overweight and obesity in adults

RC-fed Dpp4 / mice exhibited no detectable plasma DPP4 activity, an approximately 8-fold increase in plasma active GLP-1, reduced fasting glucose, improved glucose tolerance, and no difference in body weight compared with Dpp4 +/+ mice (Figure 2A and Supplemental Figure 1, A and B

Note: There are also emerging alternatives to GLP-1 medications

Personal stories reflect broader truths

BPC-157 is derived from a protective protein found in the stomach and has been studied for tissue repair and vascular repair, while TB-500 (Thymosin Beta-4 fragment) is known for its potential ability to promote cell migration, angiogenesis and recovery