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Mechanistically equivalent GH release with pharmacologically eliminated prolactin and cortisol co-stimulation , establishes Ipamorelin as the reference selective GHS-R1a agonist and the essential comparative control compound for all research seeking to distinguish GH-specific from co-secretion-dependent biological effects in the GH secretagogue pharmacology literature

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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and increased by 2.5 mg every 4 weeks up to a maintenance dose of 5-15 mg based on tolerability and therapeutic response