Oral supplements have to pass through the digestive system and may not be absorbed efficiently, especially in people with gastrointestinal conditions like celiac, Crohns, or gastritis
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Long-Term Intake of Antacids If you have gastrointestinal disorders like heartburn, peptic ulcer, or acid reflux, you may be prescribed antacids
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There is often a confusion between units: 1000 mg (milligrams) would be an extremely high and unnecessary dose, but 1000 g (micrograms) is a very standard and safe therapeutic dose for Vitamin B12