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For Wegovy, which contains semaglutide, the official guidelines are clear and consistent across regulatory bodies like the FDA and health authorities worldwide: it is prescribed as a once-weekly subcutaneous injection

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The subcutaneous administration of any medication can cause temporary irritation of nerve endings in the skin and subcutaneous tissue

Causality assessment implicated moxifloxacin as the principal offending agent, with a RUCAM score of 9 (probable) and an ALDEN score of 5 (probable)

Additionally, preclinical tendon and ligament injury models show improved fibroblast recruitment and organized collagen deposition