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Pre-clinical evidence of a dual NADPH oxidase 1/4 inhibitor (setanaxib) in liver, kidney and lung fibrosis

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The combination of GLP-1 and GIP receptor activation confers several potential advantages: Enhanced insulin secretion: Both hormones encourage pancreatic beta cells to release insulin, improving blood sugar regulation

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AFB1- exo -8,9-epoxide is then able to bind to guanine residues in DNA thus confering mutagenic properties