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Rotenone impairs autophagic flux and lysosomal functions in Parkinsons disease

In patients treated with escitalopram for 12 weeks, clinical remission was accompanied by serum reductions in neurotoxic KP metabolites, including 3-HK and QA, and a shift in metabolite ratios favouring a less excitotoxic profile (e.g., reduced QA/3-HK and increased KYNA/QA) [192]

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