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450 However, in the phase 3 IMpassion131, the combination of atezolizumab with paclitaxel did not improve PFS or OS versus paclitaxel alone in patients with locally advanced TNBC, 451 making the role of atezolizumab in advanced disease controversial and needed to be further confirmed

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The World Anti-Doping Agency (WADA) prohibits growth hormone secretagogues and GHRH and its analogs and mimetics within its hormone-and-metabolic-modulator category, and GHRH-receptor agonists such as tesamorelin and CJC-1295 are treated as prohibited substances