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There is a very strong body of experimental evidence indicating a neuroprotective role of UA, mediated through anti-inflammatory and antioxidative mechanisms that themselves are likely to be closely interrelated (summarised in Fig

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Recent assessments by the European Food Safety Authority have established increasingly stringent safety thresholds for compounds like BPA, while other regulatory agencies maintain different risk assessment frameworks, highlighting the ongoing scientific debate regarding safe exposure levels for these chemicals (149)

A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure

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