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During oocyte aging, the levels of proteins associated with mitochondrial biosynthesis, specifically SIRT1 and PGC-1, as well as those involved in mitochondrial phagocytosis, namely, PINK1 and PARKIN, are diminished

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Efferocytosis of apoptotic cells is well documented to create an immunosuppressive and inflammation-resolving microenvironment, reprogramming macrophages [239, 240]