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As we showed above, ferroptosis inhibitor Fer-1 treatment on gpx-1 (tm2100) animals, which normally displayed a high debris rate and a low fusion rate, was sufficient to decrease the debris rate and increase the fusion rate (Fig

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Pharmacol., 35 : 77-81

Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients