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Controversy exists on whether GLP-1Rs exist on pancreatic cells, with evidence pointing to an indirect effect of GLP-1RAs on glucagon inhibition

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Biochemical characteristics Peptide sequence: Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1) Molecular formula: C 50 H 69 N 15 O 9 Molecular weight: 1024.198 g/mol PubChem CID: 92432 CAS number: 121062-08-6 MT-2 is typically evaluated as a defined melanocortin agonist for receptor binding assays, signaling, and time-course studies

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