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Allergic reactions: Though extremely rare, swelling, difficulty breathing, or a rash may indicate an allergic response that requires immediate medical attention

Consultation with an endocrinologist is recommended in patients who develop elevated calcitonin concentrations or have thyroid nodules detected during imaging studies or physical exam

This underscores the importance of developing sustainable lifestyle habits during the treatment period, not relying solely on the medication for long-term results

That distinction affects safety review, labeling requirements, dosing instruction standards, and buyer due diligence obligations

Competing interests Nik Krajnc: has participated in meetings sponsored by, received speaker honoraria or travel funding from BMS/Celgene, Janssen-Cilag, Merck, Novartis, Roche and Sanofi-Genzyme and held a grant for a Multiple Sclerosis Clinical Training Fellowship Programme from the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)