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Preliminary investigations have also suggested the potential therapeutic benefits of this drug class in the treatment of AUD [18]

Huang CC, Weng SF, Tsai KT, Chen PJ, Lin HJ, Wang JJ,

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In addition to its direct antioxidant activity, L-Carnitine also has been proved to increase the expression and activity of endogenous antioxidants through the activation of PPAR- 35 , nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2) 36 , and Forkhead box O3 (FOXO3) 37 , both in vitro and in vivo