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The primary endpoint rate in the overall (non-matched) population was 20% (n = 29,032), and it was 17%, 16%, and 29%, in non-DM patients, in DM patients treated with GLP-1 RA/SGLT-2i, and in DM patients not treated with GLP-1 RA/SGLT-2i, respectively (Table 1)
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Lastly, a consensus exists that ferroptosis synergizes with other PCD types in ocular pathologies: autophagy impairment drives ferroptosis of CECs in DED, and necroptosis shares overlapping mechanisms with ferroptosis in RPE cell degeneration (90, 123)
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