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Consequently, pro-inflammatory cytokines were released into the liver (Woodhouse et al., 2018), affecting NF-B signaling pathways and histone deacetylase inhibition (Neis et al., 2016)

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FIGURE 7 3.8 Sensitivity analysis Sensitivity analysis based on the leave-one-out method for TG, TC, and HDL studies showed that excluding articles did not significantly change heterogeneity or pooled results

Whether combinations produce additive or synergistic effects across the gene-expression pathways modulated by GHK-Cu remains an open research question [12]