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Accordingly, preclinical models, mostly rodent-based, remain the main platform for assessing neuroprotective mechanisms

Goitrogens suppress the thyroid gland by suppressing the release of thyroid hormone, changing the way thyroid hormone gets produced in the body, and suppressing the absorption of iodine

In the context of lipid metabolism, targeting pathways such as ether lipid synthesis, fatty acid synthase (FASN), or the ACLY/ACC axis has been shown to induce mitochondrial stress and ROS accumulation, thereby enhancing apoptotic responses [144]

Peptide and hormone therapy should be administered under the guidance of a qualified physician

Despite their broad spectrum of antioxidant, anti-inflammatory, neuroprotective, antimicrobial, anti-diabetic, and anti-cancer activities, the therapeutic application of polyphenols is significantly hindered by their inherently poor bioavailability