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The thing is, factors such as ageing, stress and poor diet can deplete glutathione levels

Enzymes such as glutamate dehydrogenase replenish TCA intermediates and provide glutamate for GSH synthesis

The subsequent literature never converged on DSIP being a sleep-inducing agent in any conventional sense, and its own principal investigators repeatedly noted effects that had nothing to do with sleep: stress tolerance, pain, withdrawal syndromes, chronobiological regulation

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Mice were then perfused and worms were collected and counted