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Dysbiosis of the gut microbiota also leads to dysfunction of specific cellular microbiota (such as enterochromaffin cells and citrobacter ), thereby impacting the involvement of gut microbiota in the synthesis and secretion of key neurotransmitters and factors, including GABA, Glu, NE, 5-HT, and DA (Zhao et al., 2022)

Lau T, Bigio B, Zelli D, McEwen BS, Nasca C

The 85% of immunoblot positive samples and the 20-50% of indeterminate samples with core or NS3 reactivity are found to be HCV RNA positive in high HCV prevalence population.15 On the other hand, confirmed anti-HCV results are not a true indicator of an active HCV infection, since cleared patients may remain anti-HCV positive for years.17 For all these reasons, the use of a HCV RNA qualitative test to confirm the presence of an active HCV infection is more effective than any supplemental assay