Fisetin, a natural flavonoid, attenuated DOX-mediated ferroptosis in vivo and in vitro by raising the contents of GSH and GPX4 and inhibiting the accumulation of MDA and iron in the heart of rats [92]
Butyrate production in the human colon is predominantly mediated by Firmicutes microbiota, with key contributing genera including Faecalibacterium , Roseburia , Eubacterium , Anaerostipes , Butyrivibrio , and Coprococcus [13]
Biochimie 202:3448 Thangaraj A, Sil S, Tripathi A, Chivero ET, Periyasamy P, Buch S (2020) Targeting endoplasmic reticulum stress and autophagy as therapeutic approaches for neurological diseases
It is mediated by kinesin-1, which binds to mitochondria via anchoring proteins including the microtubule-associated motors dynein-dynactin, the Ca 2+ -dependent mitochondrial Rho GTPase 1 (Miro1), and the trafficking kinesin proteins 1 and 2 [45]
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